Serotype-specific Differences in Dengue Virus Non-structural Protein 5 Nuclear Localization
نویسندگان
چکیده
منابع مشابه
Serotype-specific differences in dengue virus non-structural protein 5 nuclear localization.
The four serotypes of dengue virus (DENV-1 to -4) cause the most important arthropod-borne viral disease of humans. DENV non-structural protein 5 (NS5) contains enzymatic activities required for capping and replication of the viral RNA genome that occurs in the host cytoplasm. However, previous studies have shown that DENV-2 NS5 accumulates in the nucleus during infection. In this study, we exa...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2013
ISSN: 0021-9258
DOI: 10.1074/jbc.m113.481382